Estrogens

Estrogens are a therapeutic class of endogenous, synthetic, or conjugated steroid hormones that act by binding to intracellular estrogen receptors (ER-alpha and ER-beta) to modulate gene transcription across target reproductive, vascular, skeletal, and neuroendocrine tissues By supplementing or replacing endogenous estrogen, these agents are primarily indicated for the management of menopausal vasomotor symptoms and the genitourinary syndrome of menopause, as well as the prevention of postmenopa...

Estrogens are a therapeutic class of endogenous, synthetic, or conjugated steroid hormones that act by binding to intracellular estrogen receptors (ER-alpha and ER-beta) to modulate gene transcription across target reproductive, vascular, skeletal, and neuroendocrine tissues

By supplementing or replacing endogenous estrogen, these agents are primarily indicated for the management of menopausal vasomotor symptoms and the genitourinary syndrome of menopause, as well as the prevention of postmenopausal osteoporosis

Additionally, estrogens are utilized in hormonal contraception (typically combined with a progestin), systemic treatment of female hypoestrogenism resulting from hypogonadism or primary ovarian failure, and select advanced hormone-dependent malignancies such as palliative management of prostate cancer

Additionally, estrogens are utilized in hormonal contraception (typically combined with a progestin), systemic treatment of female hypoestrogenism resulting from hypogonadism or primary ovarian failure, and select advanced hormone-dependent malignancies such as palliative management of prostate cancer