Drug class

Heparin

Heparins are a class of parenterally administered anticoagulant medications, encompassing unfractionated heparin and low-molecular-weight heparins, though the term also refers specifically to the active pharmaceutical ingredient unfractionated heparin. Read more about Heparin

88 drugs in this class 36 manufacturers

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Drugs in Heparin

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About Heparin.

Heparins are a class of parenterally administered anticoagulant medications, encompassing unfractionated heparin and low-molecular-weight heparins, though the term also refers specifically to the active pharmaceutical ingredient unfractionated heparin.

They exert their antithrombotic effect primarily by binding to and accelerating the activity of antithrombin III, which inactivates key clotting enzymes in the coagulation cascade, notably thrombin (Factor IIa) and Factor Xa, thereby suppressing fibrin formation.

Clinically, these agents are used for the prophylaxis and treatment of thromboembolic disorders such as deep vein thrombosis and pulmonary embolism, as well as for thromboembolism prevention in atrial fibrillation, acute coronary syndromes, and during cardiac surgery, extracorporeal circulation, and hemodialysis.