LIVMARLI (maralixibat chloride)
ILEAL BILE ACID TRANSPORTER (IBAT) INHIBITOR · PRURITUS DUE TO PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS ·+1
MIRUM PHARMACEU
Drug class
Ileal Bile Acid Transporter (IBAT) Inhibitor
An ileal bile acid transporter (IBAT) inhibitor, also termed an apical sodium-dependent bile acid transporter (ASBT) inhibitor, is a targeted drug class that acts locally within the lumen of the terminal ileum. Read more about Ileal Bile Acid Transporter (IBAT) Inhibitor
3 drugs in this class 3 manufacturers
Drugs in Ileal Bile Acid Transporter (IBAT) Inhibitor
BYLVAY (odevixibat)
ILEAL BILE ACID TRANSPORTER (IBAT) INHIBITOR · PRURITUS DUE TO PROGRESSIVE FAMILIAL INTRAHEPATIC CHOLESTASIS ·+1
IPSEN BIOPHARMA
LYNAVOY (linerixibat)
ILEAL BILE ACID TRANSPORTER (IBAT) INHIBITOR · BILIARY OBSTRUCTION WITH PRURITUS
INTERCEPT PHARM
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An ileal bile acid transporter (IBAT) inhibitor, also termed an apical sodium-dependent bile acid transporter (ASBT) inhibitor, is a targeted drug class that acts locally within the lumen of the terminal ileum.
Medications in this class reversibly block IBAT-mediated reabsorption of bile acids, disrupting enterohepatic recirculation and promoting fecal excretion to lower circulating serum bile acid concentrations.
Therapeutically, IBAT inhibitors are primarily indicated to manage severe cholestatic pruritus associated with rare cholestatic liver diseases, including Alagille syndrome and progressive familial intrahepatic cholestasis, as well as adult cholestatic disorders such as primary biliary cholangitis.
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fda.gov
An ileal bile acid transporter (IBAT) inhibitor, also termed an apical sodium-dependent bile acid transporter (ASBT) inhibitor, is a targeted drug class that acts locally within the lumen of the terminal ileum
-
nih.gov
An ileal bile acid transporter (IBAT) inhibitor, also termed an apical sodium-dependent bile acid transporter (ASBT) inhibitor, is a targeted drug class that acts locally within the lumen of the terminal ileum Medications in this class reversibly block IBAT-mediated reabsorption of bile acids, disrupting enterohepatic recirculation and promoting fecal excretion to lower circulating serum bile acid concentrations
-
fda.gov
Medications in this class reversibly block IBAT-mediated reabsorption of bile acids, disrupting enterohepatic recirculation and promoting fecal excretion to lower circulating serum bile acid concentrations
-
rxlist.com
Medications in this class reversibly block IBAT-mediated reabsorption of bile acids, disrupting enterohepatic recirculation and promoting fecal excretion to lower circulating serum bile acid concentrations Therapeutically, IBAT inhibitors are primarily indicated to manage severe cholestatic pruritus associated with rare cholestatic liver diseases, including Alagille syndrome and progressive familial intrahepatic cholestasis, as well as adult cholestatic disorders such as primary biliary cholangi...
-
fda.gov
Therapeutically, IBAT inhibitors are primarily indicated to manage severe cholestatic pruritus associated with rare cholestatic liver diseases, including Alagille syndrome and progressive familial intrahepatic cholestasis, as well as adult cholestatic disorders such as primary biliary cholangitis
-
govdelivery.com
Therapeutically, IBAT inhibitors are primarily indicated to manage severe cholestatic pruritus associated with rare cholestatic liver diseases, including Alagille syndrome and progressive familial intrahepatic cholestasis, as well as adult cholestatic disorders such as primary biliary cholangitis
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