CYCLOSPORINE
ANTIPSORIATICS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+2
American Regent
Drug class
Immunosuppressants - Calcineurin and mTOR Inhibitors
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)—rather than a single unified therapeutic class. Read more about Immunosuppressants - Calcineurin and mTOR Inhibitors
86 drugs in this class 54 manufacturers
Drugs in Immunosuppressants - Calcineurin and mTOR Inhibitors
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
Amneal Pharmaceuticals
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
GREENSTONE LLC.
FYARRO (sirolimus protein-bound)
ANTINEOPLASTIC - MTOR KINASE INHIBITORS · MALIGNANT PERIVASCULAR EPITHELIOID CELL TUMOR
AADI BIOSCIENCE
TORPENZ (everolimus)
ANTINEOPLASTIC - MTOR KINASE INHIBITORS · METASTATIC RENAL CELL CARCINOMA ·+6
Upsher-Smith Laboratories
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
Major Pharamceuticals
EVEROLIMUS
ANTINEOPLASTIC - MTOR KINASE INHIBITORS · METASTATIC RENAL CELL CARCINOMA ·+6
NORTHSTAR RX LL
SIROLIMUS
IMMUNOSUPPRESSANTS - MTOR INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+1
NORTHSTAR RX LL
TACROLIMUS
IMMUNOSUPPRESSANTS - CALCINEURIN INHIBITORS · PREVENTION OF KIDNEY TRANSPLANT REJECTION ·+3
NORTHSTAR RX LL
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The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)—rather than a single unified therapeutic class.
Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, and mTOR inhibitors blocking downstream cell-cycle progression.
Clinically, these agents are primarily used to prevent allograft rejection in solid organ transplantation, as well as to treat graft-versus-host disease and select severe autoimmune or inflammatory disorders.
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nih.gov
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus) Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, ...
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jebms.org
The phrase "Immunosuppressants - Calcineurin and mTOR Inhibitors" represents an administrative grouping of two distinct pharmacologic classes—calcineurin inhibitors (such as tacrolimus and cyclosporine) and mechanistic target of rapamycin (mTOR) inhibitors (such as sirolimus and everolimus)
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immunologyresearchjournal.com
Both drug categories function by disrupting intracellular signaling essential for T-lymphocyte activation and proliferation, with calcineurin inhibitors blocking cytokine transcription such as interleukin-2, and mTOR inhibitors blocking downstream cell-cycle progression
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youtube.com
Clinically, these agents are primarily used to prevent allograft rejection in solid organ transplantation, as well as to treat graft-versus-host disease and select severe autoimmune or inflammatory disorders
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