Drug class

Keratolytics (Topical), General

Keratolytics (topical, general) is a broad dermatologic drug classification encompassing agents applied directly to the skin to break down and shed excessive keratinized tissue. Read more about Keratolytics (Topical), General

135 drugs in this class 58 manufacturers

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Drugs in Keratolytics (Topical), General

Showing 100–108 of 135 drugs

UREA

KERATOLYTICS (TOPICAL), GENERAL
AVKARE

UREA

KERATOLYTICS (TOPICAL), GENERAL
AVPAK

UREA

KERATOLYTICS (TOPICAL), GENERAL
TRINITY PHARMAC

UREA

KERATOLYTICS (TOPICAL), GENERAL
METHOD PHARMACE

UREA

KERATOLYTICS (TOPICAL), GENERAL
PURETEK CORPORA

UREA

KERATOLYTICS (TOPICAL), GENERAL
BRYANT RANCH PR

UREA

KERATOLYTICS (TOPICAL), GENERAL
PALMETTO PHARMA
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About Keratolytics (Topical), General.

Keratolytics (topical, general) is a broad dermatologic drug classification encompassing agents applied directly to the skin to break down and shed excessive keratinized tissue.

While not a formal FDA-standardized therapeutic class phrase, it serves as a clinical and compendial category for agents such as urea, salicylic acid, and alpha-hydroxy acids that promote desquamation by disrupting corneocyte cohesion, softening keratin, and enhancing stratum corneum hydration.

These agents play a principal therapeutic role in reducing localized epidermal thickening and scaling, facilitating smoother skin texture and enhancing the penetration of co-administered topical therapies.

They are indicated across a spectrum of hyperkeratotic and scaling dermatoses, including psoriasis, ichthyosis, keratosis pilaris, seborrheic dermatitis, corns, calluses, and acne vulgaris.