Leukotriene Modulators

Leukotriene modulators—also commonly referred to as leukotriene modifiers—are a class of oral medications that interfere with the production or actions of leukotrienes, which are potent lipid mediators of inflammation, bronchoconstriction, mucosal edema, and mucus secretion The class comprises cysteinyl leukotriene receptor antagonists, such as montelukast and zafirlukast, which selectively block CysLT1 receptors, and 5-lipoxygenase inhibitors, such as zileuton, which halt leukotriene synthesis

Leukotriene modulators—also commonly referred to as leukotriene modifiers—are a class of oral medications that interfere with the production or actions of leukotrienes, which are potent lipid mediators of inflammation, bronchoconstriction, mucosal edema, and mucus secretion The class comprises cysteinyl leukotriene receptor antagonists, such as montelukast and zafirlukast, which selectively block CysLT1 receptors, and 5-lipoxygenase inhibitors, such as zileuton, which halt leukotriene synthesis

Therapeutically, these agents serve as long-term maintenance controllers to prevent and manage chronic asthma, prevent exercise-induced bronchoconstriction, and treat allergic rhinitis

Therapeutically, these agents serve as long-term maintenance controllers to prevent and manage chronic asthma, prevent exercise-induced bronchoconstriction, and treat allergic rhinitis

Therapeutically, these agents serve as long-term maintenance controllers to prevent and manage chronic asthma, prevent exercise-induced bronchoconstriction, and treat allergic rhinitis