SUPPRELIN LA (histrelin acetate)
LHRH(GNRH) AGONIST ANALOG PITUITARY SUPPRESSANTS · PRECOCIOUS PUBERTY
ENDO USA, INC.
Drug class
LHrH(GNrH) Agonist Analog Pituitary Suppressants
Luteinizing hormone-releasing hormone (gonadotropin-releasing hormone) agonist analog pituitary suppressants are synthetic peptide derivatives that modulate the hypothalamic-pituitary-gonadal axis. Read more about LHrH(GNrH) Agonist Analog Pituitary Suppressants
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Drugs in LHrH(GNrH) Agonist Analog Pituitary Suppressants
LEUPROLIDE ACETATE
LHRH(GNRH) AGONIST ANALOG PITUITARY SUPPRESSANTS · ADVANCED PROSTATIC CARCINOMA ·+1
ZYDUS PHARMACEU
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Luteinizing hormone-releasing hormone (gonadotropin-releasing hormone) agonist analog pituitary suppressants are synthetic peptide derivatives that modulate the hypothalamic-pituitary-gonadal axis.
Although an initial administration induces a transient surge in gonadotropin release, chronic and continuous exposure paradoxically downregulates and desensitizes pituitary receptors, profoundly suppressing luteinizing hormone and follicle-stimulating hormone secretion.
This reversible inhibition depresses circulating sex hormones to castrate or postmenopausal levels, halting hormone-driven cellular proliferation.
Consequently, these agents serve as pivotal therapies in hormone-dependent oncology settings such as advanced prostate cancer and premenopausal breast cancer, as well as in benign sex-steroid-dependent disorders including endometriosis, uterine leiomyomas, and central precocious puberty.
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fda.gov
Luteinizing hormone-releasing hormone (gonadotropin-releasing hormone) agonist analog pituitary suppressants are synthetic peptide derivatives that modulate the hypothalamic-pituitary-gonadal axis
-
nih.gov
Luteinizing hormone-releasing hormone (gonadotropin-releasing hormone) agonist analog pituitary suppressants are synthetic peptide derivatives that modulate the hypothalamic-pituitary-gonadal axis Consequently, these agents serve as pivotal therapies in hormone-dependent oncology settings such as advanced prostate cancer and premenopausal breast cancer, as well as in benign sex-steroid-dependent disorders including endometriosis, uterine leiomyomas, and central precocious puberty
-
fda.gov
Although an initial administration induces a transient surge in gonadotropin release, chronic and continuous exposure paradoxically downregulates and desensitizes pituitary receptors, profoundly suppressing luteinizing hormone and follicle-stimulating hormone secretion This reversible inhibition depresses circulating sex hormones to castrate or postmenopausal levels, halting hormone-driven cellular proliferation
-
nih.gov
Although an initial administration induces a transient surge in gonadotropin release, chronic and continuous exposure paradoxically downregulates and desensitizes pituitary receptors, profoundly suppressing luteinizing hormone and follicle-stimulating hormone secretion
-
nih.gov
This reversible inhibition depresses circulating sex hormones to castrate or postmenopausal levels, halting hormone-driven cellular proliferation
-
lbbc.org
Consequently, these agents serve as pivotal therapies in hormone-dependent oncology settings such as advanced prostate cancer and premenopausal breast cancer, as well as in benign sex-steroid-dependent disorders including endometriosis, uterine leiomyomas, and central precocious puberty
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