Methylene Blue

Rather than designating an entire therapeutic drug class, methylene blue is a specific synthetic active pharmaceutical ingredient that functions as an oxidation-reduction agent, an antidote, and a diagnostic dye Its primary established medical indication is the treatment of acquired methemoglobinemia, alongside diagnostic visualization during surgical procedures and off-label critical-care applications such as refractory vasoplegic shock

Rather than designating an entire therapeutic drug class, methylene blue is a specific synthetic active pharmaceutical ingredient that functions as an oxidation-reduction agent, an antidote, and a diagnostic dye Therapeutically, it is converted in erythrocytes to leucomethylene blue, which acts as an electron donor to reduce ferric iron back to the ferrous state, restoring the oxygen-carrying capacity of hemoglobin Its primary established medical indication is the treatment of acquired methemogl...

Therapeutically, it is converted in erythrocytes to leucomethylene blue, which acts as an electron donor to reduce ferric iron back to the ferrous state, restoring the oxygen-carrying capacity of hemoglobin Its primary established medical indication is the treatment of acquired methemoglobinemia, alongside diagnostic visualization during surgical procedures and off-label critical-care applications such as refractory vasoplegic shock