Drug class
Nasal Antihistamines
Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms. Read more about Nasal Antihistamines
33 drugs in this class 23 manufacturers
Drugs in Nasal Antihistamines
DYMISTA (azelastine HCl/fluticasone propionate)
AZELASTINE HCL
AZELASTINE HCL
PATANASE (olopatadine HCl)
RYALTRIS (olopatadine HCl/mometasone furoate)
ASTEPRO ALLERGY (azelastine HCl)
CHILDREN'S ASTEPRO ALLERGY (azelastine HCl)
AZELASTINE HCL
Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms.
They act primarily by competitively antagonizing peripheral H1 receptors on effector cells within the nasal mucosa, inhibiting histamine-mediated vasodilation, vascular permeability, and sensory nerve stimulation, while also demonstrating secondary local anti-inflammatory properties.
Clinically, they are indicated for the management of seasonal and perennial allergic rhinitis, as well as nonallergic vasomotor rhinitis, providing rapid targeted relief from rhinorrhea, sneezing, nasal pruritus, and nasal congestion with lower systemic exposure than oral alternatives.
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fda.gov
Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms
-
nih.gov
Nasal antihistamines are a therapeutic drug class consisting of topical formulations—such as azelastine and olopatadine—administered directly into the nasal passages to treat upper respiratory tract symptoms They act primarily by competitively antagonizing peripheral H1 receptors on effector cells within the nasal mucosa, inhibiting histamine-mediated vasodilation, vascular permeability, and sensory nerve stimulation, while also demonstrating secondary local anti-inflammatory properties Clinical...
-
nih.gov
They act primarily by competitively antagonizing peripheral H1 receptors on effector cells within the nasal mucosa, inhibiting histamine-mediated vasodilation, vascular permeability, and sensory nerve stimulation, while also demonstrating secondary local anti-inflammatory properties
-
fda.gov
Clinically, they are indicated for the management of seasonal and perennial allergic rhinitis, as well as nonallergic vasomotor rhinitis, providing rapid targeted relief from rhinorrhea, sneezing, nasal pruritus, and nasal congestion with lower systemic exposure than oral alternatives
-
nih.gov
Clinically, they are indicated for the management of seasonal and perennial allergic rhinitis, as well as nonallergic vasomotor rhinitis, providing rapid targeted relief from rhinorrhea, sneezing, nasal pruritus, and nasal congestion with lower systemic exposure than oral alternatives
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