Ophthalmic Antiallergic Agents

Ophthalmic antiallergic agents are a broad therapeutic class of topical ocular medications formulated to treat acute and chronic hypersensitivity reactions of the eye They encompass several pharmacologic groups, including histamine receptor antagonists, mast cell stabilizers, and dual-acting antihistamine/mast cell stabilizing agents, with selective adjuncts including vasoconstrictors, ocular NSAIDs, and corticosteroids

Ophthalmic antiallergic agents are a broad therapeutic class of topical ocular medications formulated to treat acute and chronic hypersensitivity reactions of the eye Their primary clinical applications are in the management of seasonal and perennial allergic conjunctivitis, as well as more severe forms of ocular allergy such as vernal and atopic keratoconjunctivitis

They encompass several pharmacologic groups, including histamine receptor antagonists, mast cell stabilizers, and dual-acting antihistamine/mast cell stabilizing agents, with selective adjuncts including vasoconstrictors, ocular NSAIDs, and corticosteroids

These agents work by preventing mast cell degranulation, blocking histamine-mediated vascular permeability, and suppressing the inflammatory cascade to relieve ocular pruritus, hyperemia, and conjunctival edema

These agents work by preventing mast cell degranulation, blocking histamine-mediated vascular permeability, and suppressing the inflammatory cascade to relieve ocular pruritus, hyperemia, and conjunctival edema

Their primary clinical applications are in the management of seasonal and perennial allergic conjunctivitis, as well as more severe forms of ocular allergy such as vernal and atopic keratoconjunctivitis