Drug class
Oxazolidinediones
Oxazolidinediones represent a historical class of heterocyclic anticonvulsant agents that includes compounds such as trimethadione and paramethadione. Read more about Oxazolidinediones
37 drugs in this class 25 manufacturers
Drugs in Oxazolidinediones
ZYVOX (linezolid)
ZYVOX (linezolid in dextrose 5 % in water)
LINEZOLID-0.9% NACL (linezolid in 0.9 % sodium chloride)
LINEZOLID-D5W (linezolid)
LINEZOLID-D5W (linezolid in dextrose 5 % in water)
LINEZOLID-D5W (linezolid in dextrose 5 % in water)
LINEZOLID-D5W (linezolid in dextrose 5 % in water)
ZYVOX (linezolid in dextrose 5 % in water)
Oxazolidinediones represent a historical class of heterocyclic anticonvulsant agents that includes compounds such as trimethadione and paramethadione.
Structurally related to hydantoins and succinimides, these agents exert their therapeutic effect primarily by suppressing abnormal electrical discharge in the central nervous system, principally through the reduction of low-threshold T-type calcium currents in thalamic neurons.
Clinically, oxazolidinediones were developed and indicated for the treatment of refractory absence (petit mal) seizures in epilepsy.
However, modern clinical practice rarely utilizes this class due to severe systemic toxicities and significant teratogenic risks, resulting in their displacement by safer, more effective antiseizure alternatives.
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fda.gov
Oxazolidinediones represent a historical class of heterocyclic anticonvulsant agents that includes compounds such as trimethadione and paramethadione Structurally related to hydantoins and succinimides, these agents exert their therapeutic effect primarily by suppressing abnormal electrical discharge in the central nervous system, principally through the reduction of low-threshold T-type calcium currents in thalamic neurons
-
nih.gov
Oxazolidinediones represent a historical class of heterocyclic anticonvulsant agents that includes compounds such as trimethadione and paramethadione
-
nih.gov
Structurally related to hydantoins and succinimides, these agents exert their therapeutic effect primarily by suppressing abnormal electrical discharge in the central nervous system, principally through the reduction of low-threshold T-type calcium currents in thalamic neurons However, modern clinical practice rarely utilizes this class due to severe systemic toxicities and significant teratogenic risks, resulting in their displacement by safer, more effective antiseizure alternatives
-
fda.gov
Clinically, oxazolidinediones were developed and indicated for the treatment of refractory absence (petit mal) seizures in epilepsy
-
nih.gov
Clinically, oxazolidinediones were developed and indicated for the treatment of refractory absence (petit mal) seizures in epilepsy
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