Drug class

Phosphodiesterase-4 (PDE4) inhibitors

Phosphodiesterase-4 (PDE4) inhibitors are a class of targeted anti-inflammatory agents that selectively block the intracellular enzyme phosphodiesterase-4, preventing the degradation of cyclic adenosine monophosphate (cAMP). Read more about Phosphodiesterase-4 (PDE4) inhibitors

20 drugs in this class 18 manufacturers

Advertisement

Drugs in Phosphodiesterase-4 (PDE4) inhibitors

Showing 19–20 of 20 drugs

OHTUVAYRE (ensifentrine)

PHOSPHODIESTERASE-4 (PDE4) INHIBITORS · CHRONIC OBSTRUCTIVE PULMONARY DISEASE
Merck Sharp & Dohme

ROFLUMILAST

PHOSPHODIESTERASE-4 (PDE4) INHIBITORS · PREVENTION OF BRONCHOSPASM WITH CHRONIC BRONCHITIS
AVKARE
Filter & compare in the drug finder → Opens the drug finder with Phosphodiesterase-4 (PDE4) inhibitors preselected. Add indication or manufacturer filters there.

About Phosphodiesterase-4 (PDE4) inhibitors.

Phosphodiesterase-4 (PDE4) inhibitors are a class of targeted anti-inflammatory agents that selectively block the intracellular enzyme phosphodiesterase-4, preventing the degradation of cyclic adenosine monophosphate (cAMP).

By elevating intracellular cAMP levels within immune and structural cells, these agents suppress downstream pro-inflammatory cytokines while promoting anti-inflammatory signaling cascades.

Available in oral, topical, and inhaled formulations, the class is primarily indicated for managing chronic inflammatory and autoimmune conditions across pulmonary and dermatological medicine, including chronic obstructive pulmonary disease (COPD), plaque psoriasis, psoriatic arthritis, and atopic dermatitis.