Drug class

Pulmonary Antihypertensive Agents, cGMP pathway

Pulmonary antihypertensive agents targeting the cyclic guanosine monophosphate (cGMP) pathway are cardiovascular medications that promote pulmonary vascular relaxation and reduce vascular remodeling. Read more about Pulmonary Antihypertensive Agents, cGMP pathway

84 drugs in this class 48 manufacturers

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Drugs in Pulmonary Antihypertensive Agents, cGMP pathway

Showing 46–54 of 84 drugs

TADLIQ (tadalafil)

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · PULMONARY ARTERIAL HYPERTENSION
CAROLINA MED.

ALYQ (tadalafil)

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · PULMONARY ARTERIAL HYPERTENSION
TEVA PHARM

SILDENAFIL CITRATE

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · PULMONARY ARTERIAL HYPERTENSION
Major Pharamceuticals

SILDENAFIL CITRATE

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · ERECTILE DYSFUNCTION
MACLEODS PHARMA

TADALAFIL

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · BENIGN PROSTATIC HYPERPLASIA WITH LOWER URINARY TRACT SYMPTOM ·+1
MACLEODS PHARMA

SILDENAFIL CITRATE

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · PULMONARY ARTERIAL HYPERTENSION
AVKARE

TADALAFIL

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · BENIGN PROSTATIC HYPERPLASIA WITH LOWER URINARY TRACT SYMPTOM ·+1
SOLCO HEALTHCAR

SILDENAFIL CITRATE

AGENTS TO TREAT ERECTILE DYSFUNCTION, CGMP-TYPE · PULMONARY ARTERIAL HYPERTENSION
QUALITY CARE
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About Pulmonary Antihypertensive Agents, cGMP pathway.

Pulmonary antihypertensive agents targeting the cyclic guanosine monophosphate (cGMP) pathway are cardiovascular medications that promote pulmonary vascular relaxation and reduce vascular remodeling.

They function by augmenting intracellular cGMP concentrations within pulmonary arterial smooth muscle, either by preventing its enzymatic degradation via phosphodiesterase type 5 inhibition or by directly stimulating soluble guanylate cyclase to synthesize cGMP.

By facilitating smooth muscle relaxation and lowering pulmonary vascular resistance, these agents are indicated primarily for the management of pulmonary arterial hypertension (WHO Group 1) and chronic thromboembolic pulmonary hypertension (WHO Group 4).