Drug class

Purine Analogues

Purine analogues are a class of antimetabolite medications chemically structured to mimic endogenous purine nucleosides and bases, such as adenine and guanine. Read more about Purine Analogues

75 drugs in this class 47 manufacturers

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Drugs in Purine Analogues

Showing 55–63 of 75 drugs

NELARABINE

PURINE ANALOGUES · T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ·+1
X-GEN PHARMACEU

CLADRIBINE

PURINE ANALOGUES · HAIRY CELL LEUKEMIA
HISUN-NOVAPLUS

AZATHIOPRINE

PURINE ANALOGUES · RHEUMATOID ARTHRITIS ·+1
PD-RX PHARM

AZATHIOPRINE

PURINE ANALOGUES · RHEUMATOID ARTHRITIS ·+1
AHP

NELARABINE

PURINE ANALOGUES · T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ·+1
ZYDUS USA-NOVAP

NELARABINE

PURINE ANALOGUES · T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA ·+1
Amneal Pharmaceuticals

CLADRIBINE

PURINE ANALOGUES · HAIRY CELL LEUKEMIA
Hikma Pharmaceuticals USA

AZATHIOPRINE

PURINE ANALOGUES · RHEUMATOID ARTHRITIS ·+1
GSMS, INC.
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About Purine Analogues.

Purine analogues are a class of antimetabolite medications chemically structured to mimic endogenous purine nucleosides and bases, such as adenine and guanine.

Once incorporated into target cells and metabolically activated, they disrupt cellular proliferation by competing with natural substrates, inhibiting key enzymes in purine biosynthesis and DNA replication, and causing DNA strand termination or damage.

Therapeutically, these agents are primarily indicated for the treatment of hematologic malignancies, including acute leukemias, chronic lymphocytic leukemia, and hairy cell leukemia, as well as selected autoimmune conditions like multiple sclerosis and inflammatory bowel disease.