Drug class
Rectal Local Anesthetics
Rectal local anesthetics are a route-specific functional class of topical anesthetic formulations administered to the perineal, perianal, or lower rectal mucosa. Read more about Rectal Local Anesthetics
54 drugs in this class 33 manufacturers
Drugs in Rectal Local Anesthetics
ANALPRAM HC (hydrocortisone acetate/pramoxine HCl)
PREPARATION H (phenylephrine HCl/mineral oil/petrolatum,white)
PREPARATION H (hydrocortisone)
PREPARATION H (phenylephrine HCl/pramoxine HCl/glycerin/white petrolatum)
PREPARATION H (phenylephrine HCl/witch hazel)
HEMORRHOIDAL CREAM (phenylephrine HCl/pramoxine HCl/glycerin/white petrolatum)
ANALPRAM HC (hydrocortisone acetate/pramoxine HCl)
ANA-LEX (hydrocortisone acetate/lidocaine HCl/aloe vera)
Rectal local anesthetics are a route-specific functional class of topical anesthetic formulations administered to the perineal, perianal, or lower rectal mucosa.
These agents, which commonly include lidocaine, pramoxine, and benzocaine, reversibly block voltage-gated sodium channels in sensory nerve fibers, thereby inhibiting action potential generation and transmission to numb local sensory receptors.
Clinically, they serve as symptomatic therapies to provide temporary relief of pain, pruritus, burning, and soreness associated with anorectal disorders, most notably internal and external hemorrhoids, anal fissures, and perianal excoriation.
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fda.gov
Rectal local anesthetics are a route-specific functional class of topical anesthetic formulations administered to the perineal, perianal, or lower rectal mucosa
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ecfr.gov
Rectal local anesthetics are a route-specific functional class of topical anesthetic formulations administered to the perineal, perianal, or lower rectal mucosa These agents, which commonly include lidocaine, pramoxine, and benzocaine, reversibly block voltage-gated sodium channels in sensory nerve fibers, thereby inhibiting action potential generation and transmission to numb local sensory receptors
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drugs.com
Clinically, they serve as symptomatic therapies to provide temporary relief of pain, pruritus, burning, and soreness associated with anorectal disorders, most notably internal and external hemorrhoids, anal fissures, and perianal excoriation
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rxlist.com
Clinically, they serve as symptomatic therapies to provide temporary relief of pain, pruritus, burning, and soreness associated with anorectal disorders, most notably internal and external hemorrhoids, anal fissures, and perianal excoriation
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