BEXAROTENE
SELECTIVE RETINOID X RECEPTOR AGONISTS · CUTANEOUS T-CELL LYMPHOMA
Hikma Pharmaceuticals USA
Drug class
Selective Retinoid X Receptor Agonists
Selective retinoid X receptor agonists, commonly referred to as rexinoids, are a specialized antineoplastic subclass of synthetic retinoids designed to selectively target retinoid X receptors rather than classic retinoic acid receptors. Read more about Selective Retinoid X Receptor Agonists
11 drugs in this class 10 manufacturers
Drugs in Selective Retinoid X Receptor Agonists
BEXAROTENE
SELECTIVE RETINOID X RECEPTOR AGONISTS · CUTANEOUS T-CELL LYMPHOMA
CAMBER PHARMACE
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Selective retinoid X receptor agonists, commonly referred to as rexinoids, are a specialized antineoplastic subclass of synthetic retinoids designed to selectively target retinoid X receptors rather than classic retinoic acid receptors.
By binding to RXR alpha, beta, and gamma subtypes, these agents facilitate homodimerization or heterodimerization with other nuclear receptors—such as retinoic acid, vitamin D, and peroxisome proliferator-activated receptors—to regulate transcription programs governing cellular differentiation, proliferation, and apoptosis.
Clinically, their primary established use is in oncology and dermatology, specifically for treating the manifestations of cutaneous T-cell lymphoma, with ongoing investigation into other malignancies and metabolic conditions.
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fda.gov
Selective retinoid X receptor agonists, commonly referred to as rexinoids, are a specialized antineoplastic subclass of synthetic retinoids designed to selectively target retinoid X receptors rather than classic retinoic acid receptors By binding to RXR alpha, beta, and gamma subtypes, these agents facilitate homodimerization or heterodimerization with other nuclear receptors—such as retinoic acid, vitamin D, and peroxisome proliferator-activated receptors—to regulate transcription programs gove...
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fda.gov
Selective retinoid X receptor agonists, commonly referred to as rexinoids, are a specialized antineoplastic subclass of synthetic retinoids designed to selectively target retinoid X receptors rather than classic retinoic acid receptors By binding to RXR alpha, beta, and gamma subtypes, these agents facilitate homodimerization or heterodimerization with other nuclear receptors—such as retinoic acid, vitamin D, and peroxisome proliferator-activated receptors—to regulate transcription programs gove...
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cancer.gov
Clinically, their primary established use is in oncology and dermatology, specifically for treating the manifestations of cutaneous T-cell lymphoma, with ongoing investigation into other malignancies and metabolic conditions
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