Tenofovir

Tenofovir is a specific active antiretroviral drug substance rather than an independent therapeutic drug class, belonging pharmacologically to the class of nucleotide reverse transcriptase inhibitors (NtRTIs)

Tenofovir is a specific active antiretroviral drug substance rather than an independent therapeutic drug class, belonging pharmacologically to the class of nucleotide reverse transcriptase inhibitors (NtRTIs)

Tenofovir is a specific active antiretroviral drug substance rather than an independent therapeutic drug class, belonging pharmacologically to the class of nucleotide reverse transcriptase inhibitors (NtRTIs)

Administered clinically as prodrug formulations—primarily tenofovir disoproxil fumarate or tenofovir alafenamide—it is intracellularly converted into its active diphosphate metabolite

Administered clinically as prodrug formulations—primarily tenofovir disoproxil fumarate or tenofovir alafenamide—it is intracellularly converted into its active diphosphate metabolite This active metabolite inhibits viral reverse transcriptase and viral DNA polymerase enzymes, terminating the viral DNA chain and thereby halting viral replication Agents containing tenofovir are central components in regimens utilized for the prevention and treatment of human immunodeficiency virus type 1 (HIV-1) ...

This active metabolite inhibits viral reverse transcriptase and viral DNA polymerase enzymes, terminating the viral DNA chain and thereby halting viral replication

Agents containing tenofovir are central components in regimens utilized for the prevention and treatment of human immunodeficiency virus type 1 (HIV-1) infection and the management of chronic hepatitis B virus (HBV) infection