Drug class

Thyroid Hormones

The thyroid hormones drug class comprises synthetic or naturally derived formulations of levothyroxine (tetraiodothyronine, T4) and liothyronine (triiodothyronine, T3) used to restore physiological hormone levels. Read more about Thyroid Hormones

86 drugs in this class 67 manufacturers

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About Thyroid Hormones.

The thyroid hormones drug class comprises synthetic or naturally derived formulations of levothyroxine (tetraiodothyronine, T4) and liothyronine (triiodothyronine, T3) used to restore physiological hormone levels.

These agents diffuse into cell nuclei and bind to thyroid hormone receptors, modulating gene transcription and protein synthesis to regulate basal metabolic rate, thermogenesis, cellular respiration, and tissue growth.

Clinically, they serve as foundational replacement therapy for primary, secondary, or tertiary hypothyroidism, as well as severe states such as myxedema coma.

They are also utilized to suppress pituitary thyroid-stimulating hormone secretion in the management of non-toxic goiters and as adjunctive treatment for thyrotropin-dependent differentiated thyroid carcinoma.