Drug class

Topical Antibiotics

Topical antibiotics are a route-specific therapeutic class comprising diverse antimicrobial agents formulated as creams, ointments, lotions, or solutions for direct application to the skin, ocular tissues, or mucous membranes. Read more about Topical Antibiotics

264 drugs in this class 91 manufacturers

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Drugs in Topical Antibiotics

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About Topical Antibiotics.

Topical antibiotics are a route-specific therapeutic class comprising diverse antimicrobial agents formulated as creams, ointments, lotions, or solutions for direct application to the skin, ocular tissues, or mucous membranes.

Members of this heterogenous drug class—such as mupirocin, clindamycin, erythromycin, bacitracin, and polymyxin B—exert targeted bactericidal or bacteriostatic effects by disrupting bacterial cell wall integrity, inhibiting ribosomal protein synthesis, or impairing microbial cell membrane permeability while minimizing systemic drug exposure.

They are clinically indicated for the management and prophylaxis of superficial cutaneous and mucosal bacterial infections, notably superficial skin and soft-tissue infections like impetigo, inflammatory dermatologic conditions including moderate acne vulgaris and rosacea, and localized ocular infections such as bacterial conjunctivitis.