TARGRETIN (bexarotene)
SELECTIVE RETINOID X RECEPTOR AGONISTS · CUTANEOUS T-CELL LYMPHOMA
Bausch Health US
Drug class
Topical Antineoplastic Alkylating Agents
Topical antineoplastic alkylating agents are locally administered anticancer medications designed to deliver cytotoxic therapy directly to cutaneous lesions while minimizing systemic absorption. Read more about Topical Antineoplastic Alkylating Agents
34 drugs in this class 27 manufacturers
Drugs in Topical Antineoplastic Alkylating Agents
TARGRETIN (bexarotene)
SELECTIVE RETINOID X RECEPTOR AGONISTS · CUTANEOUS T-CELL LYMPHOMA
Bausch Health US
CARAC (fluorouracil)
ACTINIC KERATOSES AGENTS · ACTINIC KERATOSIS
Bausch Health US
VALCHLOR (mechlorethamine HCl)
TOPICAL ANTINEOPLASTIC ALKYLATING AGENTS · MYCOSIS FUNGOIDES
HELSINN THERAPE
KLISYRI (tirbanibulin)
TOPICAL ANTINEOPLASTIC ALKYLATING AGENTS · ACTINIC KERATOSIS ON THE FACE OR SCALP
AQUA PHARMACEUT
PANRETIN (alitretinoin)
TOPICAL ANTINEOPLASTIC RETINOIDS · KAPOSI'S SARCOMA SKIN LESION
CONCORDIA PHARM
FLUOROURACIL
ACTINIC KERATOSES AGENTS · SUPERFICIAL BASAL CELL CARCINOMA ·+1
NORTHSTAR RX LL
FLUOROURACIL
ACTINIC KERATOSES AGENTS · SUPERFICIAL BASAL CELL CARCINOMA ·+1
ENCUBE ETHICALS
DICLOFENAC SODIUM
ACTINIC KERATOSES AGENTS · RHEUMATOID ARTHRITIS ·+2
QUALITY CARE
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Topical antineoplastic alkylating agents are locally administered anticancer medications designed to deliver cytotoxic therapy directly to cutaneous lesions while minimizing systemic absorption.
As bifunctional or polyfunctional alkylating agents—most notably mechlorethamine (nitrogen mustard)—they exert their therapeutic effect by transferring alkyl groups to cellular DNA, causing interstrand cross-linking, inhibition of DNA replication and transcription, and subsequent apoptotic cell death in rapidly proliferating malignant cells.
Therapeutically, this specialized drug class serves as skin-directed chemotherapy primarily indicated for the treatment of early-stage cutaneous T-cell lymphoma, specifically mycosis fungoides.
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oup.com
Topical antineoplastic alkylating agents are locally administered anticancer medications designed to deliver cytotoxic therapy directly to cutaneous lesions while minimizing systemic absorption Therapeutically, this specialized drug class serves as skin-directed chemotherapy primarily indicated for the treatment of early-stage cutaneous T-cell lymphoma, specifically mycosis fungoides
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nih.gov
As bifunctional or polyfunctional alkylating agents—most notably mechlorethamine (nitrogen mustard)—they exert their therapeutic effect by transferring alkyl groups to cellular DNA, causing interstrand cross-linking, inhibition of DNA replication and transcription, and subsequent apoptotic cell death in rapidly proliferating malignant cells
-
cancer.gov
As bifunctional or polyfunctional alkylating agents—most notably mechlorethamine (nitrogen mustard)—they exert their therapeutic effect by transferring alkyl groups to cellular DNA, causing interstrand cross-linking, inhibition of DNA replication and transcription, and subsequent apoptotic cell death in rapidly proliferating malignant cells
-
fda.gov
Therapeutically, this specialized drug class serves as skin-directed chemotherapy primarily indicated for the treatment of early-stage cutaneous T-cell lymphoma, specifically mycosis fungoides
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