Urinary Tract Anti-Infectives

Urinary tract anti-infectives are a functional class of antimicrobial agents characterized by their ability to concentrate in high, therapeutic levels within urine and the urinary tract while typically exerting minimal systemic antimicrobial effects

Urinary tract anti-infectives are a functional class of antimicrobial agents characterized by their ability to concentrate in high, therapeutic levels within urine and the urinary tract while typically exerting minimal systemic antimicrobial effects

These agents eradicate or suppress microbial growth through diverse mechanisms, ranging from bacterial cell wall synthesis inhibition and metabolic pathway disruption to pH-dependent conversion into nonspecifically bactericidal formaldehyde The class is primarily indicated for the treatment and prophylaxis of lower urinary tract infections, most notably acute uncomplicated cystitis and recurrent or chronic bacteriuria, while generally remaining unsuitable for systemic infections or upper urinary...