Drug class

Zidovudine

Zidovudine is a specific antiretroviral active pharmaceutical ingredient rather than an independent therapeutic drug class; it belongs to the nucleoside reverse transcriptase inhibitor class. Read more about Zidovudine

14 drugs in this class 9 manufacturers

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Drugs in Zidovudine

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About Zidovudine.

Zidovudine is a specific antiretroviral active pharmaceutical ingredient rather than an independent therapeutic drug class; it belongs to the nucleoside reverse transcriptase inhibitor class.

Functioning as a synthetic thymidine analog, the drug undergoes intracellular phosphorylation to compete with endogenous nucleotides, incorporating into viral DNA and terminating chain elongation by inhibiting the human immunodeficiency virus reverse transcriptase enzyme.

Clinically, it is utilized as part of combination antiretroviral regimens for the management of HIV-1 infection and as prophylaxis to prevent perinatal transmission from parent to infant.