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Cleocin Hcl (clindamycin HCl)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Clindamycin, a lincosamide antibiotic, is a derivative of lincomycin.

Clindamycin is used for the treatment of certain serious infections caused by susceptible aerobic gram-positive bacteria (staphylococci, streptococci, pneumococci) and for the treatment of certain serious infections caused by susceptible anaerobic bacteria. Use of clindamycin generally should be reserved for the treatment of serious infections when less toxic anti-infectives cannot be used (e.g., penicillin-allergic patients or other patients for whom a penicillin is inappropriate). Because clindamycin has been associated with potentially fatal colitis (see Cautions: GI Effects), the manufacturer recommends that clinicians consider the nature of the infection and the suitability of less toxic alternatives (e.g., erythromycin).

Generic name: clindamycin HCl
Pronunciation: (KLIN-da-MYE-sin)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Cleocin Hcl

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Indications

The following indications are listed for Cleocin Hcl:

  • Anaerobic Lung Abscess
  • Anaerobic Pelvic Cellulitis
  • Anaerobic Peritonitis
  • Anaerobic Pneumonia
  • Anaerobic Tubo-Ovarian Abscess
  • Bacterial Sepsis
  • Bacteroides Endomyometritis
  • Infectious Disease Of Abdomen
  • Inflammatory Disease Of Female Pelvic Organs
  • Intra-Abdominal Anaerobic Abscess
  • Pleural Empyema
  • Pneumococcal Pneumonia
  • Postsurgical Vaginal Cuff Anaerobic Infections
  • Sepsis Caused By Anaerobic Bacteria
  • Skin And Skin Structure Anaerobic Infection
  • Skin And Skin Structure Infection
  • Skin And Skin Structure Streptococcus Pyogenes Infection
  • Staphylococcal Pneumonia
  • Staphylococcus Aureus Skin And Skin Structure Infection
  • Streptococcal Pneumonia

Also known as: Abdominal Abscess Due To Anaerobic Bacteria, Anaerobic Sepsis, Bacteremia With Sepsis, Bacterial Septicemia, Endomyometritis Due To Bacteroides Species, Infection Of Skin And/Or Subcutaneous Tissue, Infection Of The Lungs Due To Anaerobic Bacteria, Intra-Abdominal Infection, Lung Abscess Due To Anaerobic Bacteria, Parametritis Due To Anaerobic Bacteria, Pelvic Cellulitis Due To Anaerobic Bacteria, Peritonitis Due To Anaerobic Bacteria, Pneumonia Due To Staphylococcus Species, Pneumonia Due To Staphylococcus Spp., Pneumonia Due To Streptococcus Pneumoniae, Pneumonia Due To Streptococcus Species, Pneumonia Due To Streptococcus Spp., Postsurgical Anaerobic Vaginal Cuff Infection, Pyothorax, Sepsis Of Uterine Tissue Due To Bacteroides Species, Skin & Skin Soft Tissue Streptococcus Pyogenes Infection, Skin And Skin Soft Tissue Staphylococcus Aureus Infection, Skin And Soft Tissue Skin Infection, Tubo-Ovarian Abscess Due To Anaerobic Bacteria.

Dosing

Dosage of clindamycin hydrochloride, clindamycin palmitate hydrochloride, and clindamycin phosphate is expressed in terms of clindamycin.

Dosage and duration of treatment depend on the severity of the infection. If clindamycin is used in infections caused by Streptococcus pyogenes (group A beta-hemolytic streptococci; GAS), therapy should be continued for at least 10 days. At least 6 weeks of therapy may be required for certain serious infections (e.g., osteomyelitis).

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

There is no enhanced messaging for this drug.

Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data