Abnormal uterine bleeding due to hormonal imbalance

Abnormal uterine bleeding due to hormonal imbalance refers to uterine bleeding that deviates significantly in frequency, regularity, duration, or volume from normal menstrual patterns, arising from endocrine disruption rather than structural pelvic lesions Primarily affecting reproductive-age, perimenopausal, and postpubertal adolescent females, this non-structural gynecologic condition typically stems from dysregulation of the hypothalamic-pituitary-ovarian axis

Abnormal uterine bleeding due to hormonal imbalance refers to uterine bleeding that deviates significantly in frequency, regularity, duration, or volume from normal menstrual patterns, arising from endocrine disruption rather than structural pelvic lesions Primarily affecting reproductive-age, perimenopausal, and postpubertal adolescent females, this non-structural gynecologic condition typically stems from dysregulation of the hypothalamic-pituitary-ovarian axis

Pathophysiologically, it most commonly manifests as anovulation or oligo-ovulation, leading to sustained, unopposed estrogen exposure without adequate cyclical progesterone This endocrine disturbance results in fragile, irregularly proliferative endometrium that undergoes disordered, incomplete, and often heavy or prolonged breakthrough shedding in the absence of organic pathology

Pathophysiologically, it most commonly manifests as anovulation or oligo-ovulation, leading to sustained, unopposed estrogen exposure without adequate cyclical progesterone

This endocrine disturbance results in fragile, irregularly proliferative endometrium that undergoes disordered, incomplete, and often heavy or prolonged breakthrough shedding in the absence of organic pathology