Indication

Acute gonococcal endometritis

Acute gonococcal endometritis is an acute, sexually transmitted bacterial infection of the inner mucosal lining of the uterus, occurring as an upper genital tract manifestation of pelvic inflammatory disease in adolescent and adult females. Read more about Acute gonococcal endometritis

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About Acute gonococcal endometritis.

Acute gonococcal endometritis is an acute, sexually transmitted bacterial infection of the inner mucosal lining of the uterus, occurring as an upper genital tract manifestation of pelvic inflammatory disease in adolescent and adult females.

It develops when the Gram-negative diplococcus *Neisseria gonorrhoeae* ascends from an untreated or underdiagnosed infection of the cervix into the uterine cavity.

Pathophysiologically, the pathogen invades the endometrial mucosa and elicits a vigorous innate immune response characterized by marked neutrophilic infiltration, tissue edema, and mucosal microabscesses.

Clinically, affected individuals typically present with the abrupt onset of lower abdominal and pelvic pain, abnormal uterine bleeding, mucopurulent vaginal discharge, uterine tenderness on examination, and systemic signs such as fever.

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