Agitation associated with bipolar mania

Agitation associated with bipolar mania is an acute neurobehavioral state occurring in individuals experiencing a manic or mixed episode of bipolar disorder If untreated, this state can rapidly escalate along a behavioral continuum to heightened hostility, uncooperativeness, impulsivity, and verbal or physical aggression, posing safety risks to the patient and others

Agitation associated with bipolar mania is an acute neurobehavioral state occurring in individuals experiencing a manic or mixed episode of bipolar disorder

Pathophysiologically linked to central nervous system dysregulation involving monoaminergic neurotransmission and impaired frontolimbic circuitry, it affects emotional and motor control

Pathophysiologically linked to central nervous system dysregulation involving monoaminergic neurotransmission and impaired frontolimbic circuitry, it affects emotional and motor control Clinically, it is characterized by profound internal tension, severe restlessness, emotional lability, irritability, and non-purposeful or excessive psychomotor activity, such as pacing or hand-wringing If untreated, this state can rapidly escalate along a behavioral continuum to heightened hostility, uncooperati...

Clinically, it is characterized by profound internal tension, severe restlessness, emotional lability, irritability, and non-purposeful or excessive psychomotor activity, such as pacing or hand-wringing If untreated, this state can rapidly escalate along a behavioral continuum to heightened hostility, uncooperativeness, impulsivity, and verbal or physical aggression, posing safety risks to the patient and others