Alcohol withdrawal delirium

Alcohol withdrawal delirium, clinically known as delirium tremens, is an acute, severe neuropsychiatric complication of alcohol withdrawal syndrome that predominantly affects adults with chronic alcohol dependence following the abrupt reduction or cessation of heavy alcohol intake Clinically, the condition manifests roughly 48 to 96 hours after the last drink with fluctuating clouding of consciousness, disorientation, vivid hallucinations, pronounced psychomotor agitation, and severe autonomic h...

Alcohol withdrawal delirium, clinically known as delirium tremens, is an acute, severe neuropsychiatric complication of alcohol withdrawal syndrome that predominantly affects adults with chronic alcohol dependence following the abrupt reduction or cessation of heavy alcohol intake Pathophysiologically, it stems from a profound neurochemical rebound characterized by diminished gamma-aminobutyric acid (GABA) inhibitory tone and enhanced glutamate-mediated excitatory activity via N-methyl-D-asparta...

Clinically, the condition manifests roughly 48 to 96 hours after the last drink with fluctuating clouding of consciousness, disorientation, vivid hallucinations, pronounced psychomotor agitation, and severe autonomic hyperactivity such as tachycardia, hypertension, diaphoresis, hyperthermia, and tremors