Alopecia areata

Alopecia areata is a chronic, immune-mediated dermatologic disorder characterized by non-scarring hair loss that can affect any hair-bearing surface in children and adults Clinically, it most often manifests as smooth, sharply demarcated, round or oval patches of sudden hair loss primarily on the scalp, accompanied by trichoscopic findings such as exclamation point hairs and occasional nail dystrophy

Alopecia areata is a chronic, immune-mediated dermatologic disorder characterized by non-scarring hair loss that can affect any hair-bearing surface in children and adults Pathophysiologically, it is driven by a breakdown of hair follicle immune privilege, leading to lymphocytic infiltration around anagen hair bulbs, follicular disruption, and premature transition into the telogen phase while sparing the follicular stem cells Although the course is often relapsing and remitting, severe presentat...

Pathophysiologically, it is driven by a breakdown of hair follicle immune privilege, leading to lymphocytic infiltration around anagen hair bulbs, follicular disruption, and premature transition into the telogen phase while sparing the follicular stem cells Clinically, it most often manifests as smooth, sharply demarcated, round or oval patches of sudden hair loss primarily on the scalp, accompanied by trichoscopic findings such as exclamation point hairs and occasional nail dystrophy