Indication

Anaerobic joint infection

An anaerobic joint infection is a septic inflammation of a native synovial articulation or prosthetic joint caused by obligate or microaerophilic anaerobic microorganisms. Read more about Anaerobic joint infection

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About Anaerobic joint infection.

An anaerobic joint infection is a septic inflammation of a native synovial articulation or prosthetic joint caused by obligate or microaerophilic anaerobic microorganisms.

Primarily affecting the musculoskeletal system, it frequently manifests in large weight-bearing joints, such as the hips and knees, with heightened incidence among patients following orthopedic surgery, joint arthroplasty, penetrating trauma, or hematogenous seeding from intra-abdominal, pelvic, or odontogenic sources.

Pathophysiologically, common pathogens—including *Cutibacterium* (formerly *Propionibacterium*) *acnes*, *Bacteroides fragilis*, *Finegoldia magna*, *Peptostreptococcus*, and *Fusobacterium* species—infiltrate the synovial cavity, triggering inflammatory purulence, synovial necrosis, and progressive destruction of articular cartilage or bone.

Clinically, these infections may present indolently or acutely with localized pain, swelling, erythema, restricted range of motion, and occasionally foul-smelling purulent synovial effusions or implant loosening.

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