Aspergillosis

Aspergillosis is a spectrum of fungal diseases caused by ubiquitous environmental molds of the genus *Aspergillus*, most frequently *Aspergillus fumigatus* It primarily affects the respiratory system—including the lungs and paranasal sinuses—predisposing individuals with underlying pulmonary conditions or impaired host immunity The clinical and pathophysiologic manifestations depend on immune status, ranging from hypersensitivity reactions such as allergic bronchopulmonary aspergillosis in patie...

Aspergillosis is a spectrum of fungal diseases caused by ubiquitous environmental molds of the genus *Aspergillus*, most frequently *Aspergillus fumigatus* It primarily affects the respiratory system—including the lungs and paranasal sinuses—predisposing individuals with underlying pulmonary conditions or impaired host immunity The clinical and pathophysiologic manifestations depend on immune status, ranging from hypersensitivity reactions such as allergic bronchopulmonary aspergillosis in patie...

The clinical and pathophysiologic manifestations depend on immune status, ranging from hypersensitivity reactions such as allergic bronchopulmonary aspergillosis in patients with asthma or cystic fibrosis, to noninvasive fungus balls (aspergillomas) in pre-existing pulmonary cavities, and angioinvasive, life-threatening tissue destruction with potential hematogenous dissemination in severely immunocompromised hosts