Bartonellosis

Bartonellosis refers to a group of zoonotic and vector-borne infectious diseases caused by facultative intracellular, gram-negative bacteria of the genus *Bartonella*, primarily *B. henselae*, *B. quintana*, and *B. bacilliformis* The infection primarily targets the reticuloendothelial, vascular endothelial, and hematologic systems, manifesting across diverse patient populations ranging from healthy hosts to severely immunocompromised individuals Pathophysiologically, the bacteria parasitize ery...

Bartonellosis refers to a group of zoonotic and vector-borne infectious diseases caused by facultative intracellular, gram-negative bacteria of the genus *Bartonella*, primarily *B. henselae*, *B. quintana*, and *B. bacilliformis* Pathophysiologically, the bacteria parasitize erythrocytes and induce endothelial cell proliferation and angiogenesis

The infection primarily targets the reticuloendothelial, vascular endothelial, and hematologic systems, manifesting across diverse patient populations ranging from healthy hosts to severely immunocompromised individuals

Clinical presentations vary by species and immune status, encompassing self-limiting regional lymphadenopathy and fever (cat-scratch disease), relapsing febrile bacteremia (trench fever), hemolytic anemia and eruptive angiomatous skin lesions (Carrión disease), as well as invasive complications such as culture-negative endocarditis, bacillary angiomatosis, and peliosis hepatis