Candidemia

Candidemia is a serious bloodstream infection defined by the presence of viable *Candida* species in circulating blood, representing the most common manifestation of invasive candidiasis The condition predominantly affects hospitalized and immunocompromised individuals, including intensive care unit patients, low-birth-weight neonates, and persons with indwelling vascular catheters, recent major surgery, or prolonged exposure to broad-spectrum antibiotics Pathophysiologically, commensal *Candida...

Candidemia is a serious bloodstream infection defined by the presence of viable *Candida* species in circulating blood, representing the most common manifestation of invasive candidiasis Pathophysiologically, commensal *Candida* yeasts translocate across disrupted mucosal or cutaneous barriers, enter the intravascular space, and disseminate hematogenously

The condition predominantly affects hospitalized and immunocompromised individuals, including intensive care unit patients, low-birth-weight neonates, and persons with indwelling vascular catheters, recent major surgery, or prolonged exposure to broad-spectrum antibiotics Clinically, it manifests with persistent fever, chills, and features of systemic inflammatory response or septic shock, carrying a significant risk of secondary metastatic seeding into deep tissues such as the retina, endocardi...