Carcinoma of breast

Carcinoma of the breast is a malignant epithelial neoplasm that originates in the glandular structures of the breast tissue, predominantly arising from the lining of the lactiferous ducts (ductal carcinoma) or the milk-producing lobules (lobular carcinoma)

Carcinoma of the breast is a malignant epithelial neoplasm that originates in the glandular structures of the breast tissue, predominantly arising from the lining of the lactiferous ducts (ductal carcinoma) or the milk-producing lobules (lobular carcinoma) Clinically, it frequently presents as a painless, palpable breast mass, focal tissue thickening, or abnormal findings on screening mammography, with advanced presentations occasionally demonstrating nipple retraction, skin dimpling, or spontan...

It predominantly affects adult females, though it can also occur in males Pathophysiologically, the disease is characterized by unregulated epithelial proliferation that may remain confined to the basement membrane as carcinoma in situ or breach surrounding tissue planes as invasive disease, carrying the potential to disseminate via regional lymphatic channels and hematogenous pathways to distant organs

It predominantly affects adult females, though it can also occur in males Clinically, it frequently presents as a painless, palpable breast mass, focal tissue thickening, or abnormal findings on screening mammography, with advanced presentations occasionally demonstrating nipple retraction, skin dimpling, or spontaneous nipple discharge

Pathophysiologically, the disease is characterized by unregulated epithelial proliferation that may remain confined to the basement membrane as carcinoma in situ or breach surrounding tissue planes as invasive disease, carrying the potential to disseminate via regional lymphatic channels and hematogenous pathways to distant organs

Clinically, it frequently presents as a painless, palpable breast mass, focal tissue thickening, or abnormal findings on screening mammography, with advanced presentations occasionally demonstrating nipple retraction, skin dimpling, or spontaneous nipple discharge