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Indication

Chronic hepatitis B

Chronic hepatitis B is a persistent infection of the liver caused by the hepatitis B virus (HBV), serologically defined by the presence of hepatitis B surface antigen (HBsAg) in the blood for at least six months. Read more about Chronic hepatitis B

53 drugs 38 manufacturers

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Drugs that treat it

Common Chronic hepatitis B therapies.

Showing 19–27 of 53 drugs

ENTECAVIR

CHRONIC HEPATITIS B·+1
CIPLA USA, INC.

ENTECAVIR

CHRONIC HEPATITIS B·+1
ACCORD HEALTHCA
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About Chronic hepatitis B.

Chronic hepatitis B is a persistent infection of the liver caused by the hepatitis B virus (HBV), serologically defined by the presence of hepatitis B surface antigen (HBsAg) in the blood for at least six months.

Pathophysiologically, the viral genome establishes covalently closed circular DNA (cccDNA) within host hepatocytes, where host immune-mediated responses rather than direct viral cytopathology drive hepatic necroinflammation.

The condition encompasses a dynamic clinical spectrum ranging from asymptomatic, inactive carrier states to active hepatitis marked by elevated serum alanine aminotransferase and circulating HBV DNA.

Left untreated, progressive chronic necroinflammation significantly elevates the risk of severe hepatic complications, including progressive fibrosis, cirrhosis, hepatic decompensation, and hepatocellular carcinoma.

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