Chronic rhinosinusitis with nasal polyposis

Chronic rhinosinusitis with nasal polyposis is a chronic inflammatory disorder of the paranasal sinuses and nasal passages, characterized by persistent mucosal inflammation lasting twelve weeks or longer accompanied by the development of benign, bilateral fleshy outgrowths called nasal polyps Patients typically present with prominent nasal congestion or obstruction, anterior or posterior rhinorrhea, facial pressure, and a marked reduction or loss of smell

Chronic rhinosinusitis with nasal polyposis is a chronic inflammatory disorder of the paranasal sinuses and nasal passages, characterized by persistent mucosal inflammation lasting twelve weeks or longer accompanied by the development of benign, bilateral fleshy outgrowths called nasal polyps Patients typically present with prominent nasal congestion or obstruction, anterior or posterior rhinorrhea, facial pressure, and a marked reduction or loss of smell

Primarily affecting adults, the condition frequently involves a predominantly type 2 immune response marked by tissue eosinophilia and epithelial barrier disruption

Primarily affecting adults, the condition frequently involves a predominantly type 2 immune response marked by tissue eosinophilia and epithelial barrier disruption

The diagnosis is confirmed by objective demonstration of mucosal polyps and sinus opacification via anterior rhinoscopy, nasal endoscopy, or computed tomography imaging

The diagnosis is confirmed by objective demonstration of mucosal polyps and sinus opacification via anterior rhinoscopy, nasal endoscopy, or computed tomography imaging