Citrobacter septicemia

Citrobacter septicemia is a severe, systemic bloodstream infection caused by opportunistic Gram-negative bacilli of the genus *Citrobacter*, most commonly *Citrobacter freundii* or *Citrobacter koseri* It predominantly affects hospitalized, immunocompromised individuals, neonates, and patients with significant underlying comorbidities such as hepatobiliary disease, malignancy, or indwelling medical devices Pathophysiologically, bacteria translocate into the vascular compartment—often originating...

Citrobacter septicemia is a severe, systemic bloodstream infection caused by opportunistic Gram-negative bacilli of the genus *Citrobacter*, most commonly *Citrobacter freundii* or *Citrobacter koseri*

Citrobacter septicemia is a severe, systemic bloodstream infection caused by opportunistic Gram-negative bacilli of the genus *Citrobacter*, most commonly *Citrobacter freundii* or *Citrobacter koseri*

It predominantly affects hospitalized, immunocompromised individuals, neonates, and patients with significant underlying comorbidities such as hepatobiliary disease, malignancy, or indwelling medical devices The condition is clinically defined by positive blood cultures accompanied by systemic manifestations including fever, tachycardia, tachypnea, and leukocytosis, which can rapidly deteriorate into septic shock, multi-organ dysfunction, and, particularly in infants, metastatic central nervous ...

It predominantly affects hospitalized, immunocompromised individuals, neonates, and patients with significant underlying comorbidities such as hepatobiliary disease, malignancy, or indwelling medical devices Pathophysiologically, bacteria translocate into the vascular compartment—often originating from primary intra-abdominal, urinary, or respiratory tract foci—triggering dysregulated systemic inflammatory responses The condition is clinically defined by positive blood cultures accompanied by sy...

The condition is clinically defined by positive blood cultures accompanied by systemic manifestations including fever, tachycardia, tachypnea, and leukocytosis, which can rapidly deteriorate into septic shock, multi-organ dysfunction, and, particularly in infants, metastatic central nervous system complications such as cerebritis or brain abscesses