CMV retinitis in AIDS patient

Cytomegalovirus retinitis in an AIDS patient is a sight-threatening opportunistic ocular infection caused by the reactivation of human cytomegalovirus in individuals with advanced acquired immunodeficiency syndrome, classically occurring when CD4+ T-lymphocyte counts drop below 50 cells/µL The condition primarily impacts the retina and posterior segment of the eye through hematogenous viral spread and cell-to-cell transmission It is clinically characterized by necrotizing full-thickness retiniti...

Cytomegalovirus retinitis in an AIDS patient is a sight-threatening opportunistic ocular infection caused by the reactivation of human cytomegalovirus in individuals with advanced acquired immunodeficiency syndrome, classically occurring when CD4+ T-lymphocyte counts drop below 50 cells/µL

The condition primarily impacts the retina and posterior segment of the eye through hematogenous viral spread and cell-to-cell transmission

It is clinically characterized by necrotizing full-thickness retinitis, retinal hemorrhages, perivascular sheathing, and minimal vitreous inflammation, which present with floaters, scotomas, or progressive painless visual field loss that can advance to rhegmatogenous retinal detachment and irreversible blindness if left untreated