Crohn's disease

Crohn’s disease is a chronic inflammatory bowel disease characterized by progressive, transmural inflammation that can involve any portion of the gastrointestinal tract, most commonly affecting the terminal ileum and colon

Crohn’s disease is a chronic inflammatory bowel disease characterized by progressive, transmural inflammation that can involve any portion of the gastrointestinal tract, most commonly affecting the terminal ileum and colon It typically follows a relapsing and remitting course marked by patchy "skip lesions," abdominal pain, chronic diarrhea, fatigue, and weight loss

It typically follows a relapsing and remitting course marked by patchy "skip lesions," abdominal pain, chronic diarrhea, fatigue, and weight loss Pathophysiologically driven by immune dysregulation, genetic susceptibility, and environmental factors, the transmural nature of the inflammation frequently leads to structural complications such as strictures, fistulas, abscesses, and bowel obstructions