Delayed puberty

Delayed puberty is an endocrine and developmental condition characterized by the absence of expected secondary sexual characteristics at an age greater than two to 2.5 standard deviations above the population mean It affects adolescents and is clinically defined by the lack of breast development in girls by age 13 or the absence of testicular enlargement (testicular volume less than 4 mL) in boys by age 14, as well as an arrest in pubertal progression Pathophysiologically, the disorder stems fro...

Delayed puberty is an endocrine and developmental condition characterized by the absence of expected secondary sexual characteristics at an age greater than two to 2.5 standard deviations above the population mean It affects adolescents and is clinically defined by the lack of breast development in girls by age 13 or the absence of testicular enlargement (testicular volume less than 4 mL) in boys by age 14, as well as an arrest in pubertal progression

It affects adolescents and is clinically defined by the lack of breast development in girls by age 13 or the absence of testicular enlargement (testicular volume less than 4 mL) in boys by age 14, as well as an arrest in pubertal progression

Pathophysiologically, the disorder stems from delayed or impaired activation of the hypothalamic-pituitary-gonadal axis Pathophysiologically, the disorder stems from delayed or impaired activation of the hypothalamic-pituitary-gonadal axis, which may result from self-limited constitutional delay of growth and puberty, functional hypogonadotropic hypogonadism due to systemic illness, permanent central gonadotropin deficiency, or primary gonadal failure

Pathophysiologically, the disorder stems from delayed or impaired activation of the hypothalamic-pituitary-gonadal axis, which may result from self-limited constitutional delay of growth and puberty, functional hypogonadotropic hypogonadism due to systemic illness, permanent central gonadotropin deficiency, or primary gonadal failure

Pathophysiologically, the disorder stems from delayed or impaired activation of the hypothalamic-pituitary-gonadal axis, which may result from self-limited constitutional delay of growth and puberty, functional hypogonadotropic hypogonadism due to systemic illness, permanent central gonadotropin deficiency, or primary gonadal failure