Diarrhea predominant irritable bowel syndrome

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a chronic disorder of gut-brain interaction affecting the gastrointestinal system, primarily presenting in adolescents and adults with a higher prevalence in females The underlying pathophysiology is multifactorial and involves dysregulated gut-brain signaling, accelerated intestinal transit, visceral hypersensitivity, altered gut microbiota, and increased intestinal mucosal permeability

Diarrhea-predominant irritable bowel syndrome (IBS-D) is a chronic disorder of gut-brain interaction affecting the gastrointestinal system, primarily presenting in adolescents and adults with a higher prevalence in females

It is clinically characterized by recurrent abdominal pain related to defecation, accompanied by frequent, loose, or watery stools on more than 25% of bowel movement days without predominant constipation

It is clinically characterized by recurrent abdominal pain related to defecation, accompanied by frequent, loose, or watery stools on more than 25% of bowel movement days without predominant constipation The underlying pathophysiology is multifactorial and involves dysregulated gut-brain signaling, accelerated intestinal transit, visceral hypersensitivity, altered gut microbiota, and increased intestinal mucosal permeability