Discoid lupus erythematosus

Discoid lupus erythematosus is a chronic autoimmune dermatologic condition representing the most common subtype of chronic cutaneous lupus erythematosus It predominantly affects the integumentary system—most often appearing in women on sun-exposed regions such as the scalp, face, and ears—either as an isolated cutaneous disease or as a cutaneous manifestation of systemic lupus erythematosus Pathophysiologically, localized interface dermatitis and autoimmune inflammation produce well-demarcated, ...

Discoid lupus erythematosus is a chronic autoimmune dermatologic condition representing the most common subtype of chronic cutaneous lupus erythematosus Pathophysiologically, localized interface dermatitis and autoimmune inflammation produce well-demarcated, disc-shaped erythematous plaques that display adherent follicular hyperkeratotic scaling and telangiectasias, which classically evolve over time into cutaneous atrophy, dyspigmentation, scarring, and permanent scarring alopecia

It predominantly affects the integumentary system—most often appearing in women on sun-exposed regions such as the scalp, face, and ears—either as an isolated cutaneous disease or as a cutaneous manifestation of systemic lupus erythematosus

It predominantly affects the integumentary system—most often appearing in women on sun-exposed regions such as the scalp, face, and ears—either as an isolated cutaneous disease or as a cutaneous manifestation of systemic lupus erythematosus

Pathophysiologically, localized interface dermatitis and autoimmune inflammation produce well-demarcated, disc-shaped erythematous plaques that display adherent follicular hyperkeratotic scaling and telangiectasias, which classically evolve over time into cutaneous atrophy, dyspigmentation, scarring, and permanent scarring alopecia

Pathophysiologically, localized interface dermatitis and autoimmune inflammation produce well-demarcated, disc-shaped erythematous plaques that display adherent follicular hyperkeratotic scaling and telangiectasias, which classically evolve over time into cutaneous atrophy, dyspigmentation, scarring, and permanent scarring alopecia