Indication

E. coli joint infection

An *Escherichia coli* joint infection, or *E. Read more about E. coli joint infection

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About E. coli joint infection.

An *Escherichia coli* joint infection, or *E.

coli* septic arthritis, is an uncommon and destructive bacterial infection of the synovial fluid and articular tissues caused by the Gram-negative bacillus *E.

coli*.

It most frequently affects the musculoskeletal system of older adults, immunocompromised individuals, or patients with prosthetic hardware, often arising via hematogenous dissemination from an underlying urinary tract or intra-abdominal source.

Pathophysiologically, bacterial invasion triggers intense intra-articular inflammation characterized by marked synovial fluid leukocytosis, articular cartilage degradation, and bone erosion.

Defining clinical features typically include acute monoarticular joint pain, marked effusion, warmth, erythema, severely restricted range of motion, and fever.

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