Edema due to hepatic cirrhosis

Edema due to hepatic cirrhosis is a clinical manifestation of decompensated chronic liver disease characterized by pathologic accumulation of extracellular fluid, presenting as ascites, dependent peripheral edema, or anasarca

Edema due to hepatic cirrhosis is a clinical manifestation of decompensated chronic liver disease characterized by pathologic accumulation of extracellular fluid, presenting as ascites, dependent peripheral edema, or anasarca It arises primarily from portal hypertension and impaired hepatic synthetic function, which lead to decreased serum albumin and reduced intravascular oncotic pressure Affected patients display visible abdominal distension and lower extremity swelling, signifying systemic he...

Edema due to hepatic cirrhosis is a clinical manifestation of decompensated chronic liver disease characterized by pathologic accumulation of extracellular fluid, presenting as ascites, dependent peripheral edema, or anasarca

It arises primarily from portal hypertension and impaired hepatic synthetic function, which lead to decreased serum albumin and reduced intravascular oncotic pressure Splanchnic arterial vasodilation concurrently reduces effective circulating arterial volume, triggering secondary neurohormonal activation—predominantly the renin-angiotensin-aldosterone system, sympathetic nervous system, and arginine vasopressin release—that drives avid renal sodium and water retention

It arises primarily from portal hypertension and impaired hepatic synthetic function, which lead to decreased serum albumin and reduced intravascular oncotic pressure Affected patients display visible abdominal distension and lower extremity swelling, signifying systemic hemodynamic dysfunction and advanced hepatic failure

Splanchnic arterial vasodilation concurrently reduces effective circulating arterial volume, triggering secondary neurohormonal activation—predominantly the renin-angiotensin-aldosterone system, sympathetic nervous system, and arginine vasopressin release—that drives avid renal sodium and water retention Affected patients display visible abdominal distension and lower extremity swelling, signifying systemic hemodynamic dysfunction and advanced hepatic failure