Encephalitis due to toxoplasmosis

Encephalitis due to toxoplasmosis is an opportunistic central nervous system infection caused by the obligate intracellular protozoan parasite *Toxoplasma gondii*

Encephalitis due to toxoplasmosis is an opportunistic central nervous system infection caused by the obligate intracellular protozoan parasite *Toxoplasma gondii* It primarily occurs in severely immunocompromised individuals, most notably patients with advanced HIV infection or AIDS—where it serves as an AIDS-defining illness—as well as solid-organ and hematopoietic stem cell transplant recipients Clinically, it manifests as subacute necrotizing encephalitis marked by fever, headache, altered me...

It primarily occurs in severely immunocompromised individuals, most notably patients with advanced HIV infection or AIDS—where it serves as an AIDS-defining illness—as well as solid-organ and hematopoietic stem cell transplant recipients

It primarily occurs in severely immunocompromised individuals, most notably patients with advanced HIV infection or AIDS—where it serves as an AIDS-defining illness—as well as solid-organ and hematopoietic stem cell transplant recipients

Pathophysiologically, the disease typically arises from the reactivation of latent encysted bradyzoites within brain tissue into rapidly multiplying, lytic tachyzoites when cellular immunity wanes

Pathophysiologically, the disease typically arises from the reactivation of latent encysted bradyzoites within brain tissue into rapidly multiplying, lytic tachyzoites when cellular immunity wanes

Clinically, it manifests as subacute necrotizing encephalitis marked by fever, headache, altered mental status, seizures, and focal neurological deficits, characteristically presenting on neuroimaging with multiple ring-enhancing brain lesions and surrounding vasogenic edema

Clinically, it manifests as subacute necrotizing encephalitis marked by fever, headache, altered mental status, seizures, and focal neurological deficits, characteristically presenting on neuroimaging with multiple ring-enhancing brain lesions and surrounding vasogenic edema