H. influenzae meningitis

*H. influenzae* meningitis is a severe, life-threatening bacterial infection characterized by acute purulent inflammation of the meninges surrounding the brain and spinal cord Caused by the gram-negative coccobacillus *Haemophilus influenzae*—historically most often encapsulated serotype b (Hib)—it primarily targets infants, children under five years of age, and immunocompromised or asplenic individuals following hematogenous dissemination from the upper respiratory tract Hallmarks of the diseas...

*H. influenzae* meningitis is a severe, life-threatening bacterial infection characterized by acute purulent inflammation of the meninges surrounding the brain and spinal cord

Caused by the gram-negative coccobacillus *Haemophilus influenzae*—historically most often encapsulated serotype b (Hib)—it primarily targets infants, children under five years of age, and immunocompromised or asplenic individuals following hematogenous dissemination from the upper respiratory tract

Caused by the gram-negative coccobacillus *Haemophilus influenzae*—historically most often encapsulated serotype b (Hib)—it primarily targets infants, children under five years of age, and immunocompromised or asplenic individuals following hematogenous dissemination from the upper respiratory tract Without prompt intervention, the inflammatory response in the subarachnoid space can lead to elevated intracranial pressure, subdural effusions, irreversible sensorineural hearing loss, or death

Hallmarks of the disease include high fever, severe headache, nuchal rigidity, photophobia, altered mental status, and, in infants, poor feeding, lethargy, and bulging fontanelles

Without prompt intervention, the inflammatory response in the subarachnoid space can lead to elevated intracranial pressure, subdural effusions, irreversible sensorineural hearing loss, or death