Herpes simplex infection

Herpes simplex infection is a prevalent, lifelong viral condition caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) Clinical reactivations occur intermittently when the latent virus travels back to the epithelial surface, resulting in either symptomatic recurrent outbreaks or asymptomatic viral shedding

Herpes simplex infection is a prevalent, lifelong viral condition caused by herpes simplex virus type 1 (HSV-1) or type 2 (HSV-2) The pathogen primarily affects the mucocutaneous membranes and the nervous system, typically manifesting as oral or genital lesions, but it can also cause ocular, cutaneous, or central nervous system disease, with increased risk for severe complications in neonates and immunocompromised individuals Pathophysiologically, the virus replicates locally in epithelial cells...

The pathogen primarily affects the mucocutaneous membranes and the nervous system, typically manifesting as oral or genital lesions, but it can also cause ocular, cutaneous, or central nervous system disease, with increased risk for severe complications in neonates and immunocompromised individuals Pathophysiologically, the virus replicates locally in epithelial cells—producing characteristic clusters of painful, fluid-filled vesicles that ulcerate and crust—before migrating via sensory neurons ...

Clinical reactivations occur intermittently when the latent virus travels back to the epithelial surface, resulting in either symptomatic recurrent outbreaks or asymptomatic viral shedding