Infantile spasms

Infantile spasms represent a severe, age-specific epileptic encephalopathy of infancy and early childhood, predominantly emerging within the first year of life with peak onset between three and seven months of age Pathophysiologically, it is strongly associated with an interictal electroencephalographic pattern known as hypsarrhythmia, driven by abnormal cortical-subcortical neuronal interactions Frequently arising from structural brain malformations, genetic disorders, tuberous sclerosis, or hy...

Infantile spasms represent a severe, age-specific epileptic encephalopathy of infancy and early childhood, predominantly emerging within the first year of life with peak onset between three and seven months of age

Infantile spasms represent a severe, age-specific epileptic encephalopathy of infancy and early childhood, predominantly emerging within the first year of life with peak onset between three and seven months of age Pathophysiologically, it is strongly associated with an interictal electroencephalographic pattern known as hypsarrhythmia, driven by abnormal cortical-subcortical neuronal interactions

The central nervous system condition is clinically characterized by brief, sudden contractions of the neck, trunk, and extremities—manifesting as flexor, extensor, or mixed jerks—that typically occur in repetitive clusters

The central nervous system condition is clinically characterized by brief, sudden contractions of the neck, trunk, and extremities—manifesting as flexor, extensor, or mixed jerks—that typically occur in repetitive clusters

Frequently arising from structural brain malformations, genetic disorders, tuberous sclerosis, or hypoxic-ischemic insults, infantile spasms can cause marked developmental arrest or psychomotor regression

Frequently arising from structural brain malformations, genetic disorders, tuberous sclerosis, or hypoxic-ischemic insults, infantile spasms can cause marked developmental arrest or psychomotor regression