Infection of burn wound

An infection of a burn wound is an infectious complication affecting the integumentary system that occurs when microbial pathogens—most commonly opportunistic bacteria or fungi—colonize and proliferate within thermally damaged tissue

An infection of a burn wound is an infectious complication affecting the integumentary system that occurs when microbial pathogens—most commonly opportunistic bacteria or fungi—colonize and proliferate within thermally damaged tissue

It primarily affects pediatric and adult patients recovering from partial- or full-thickness thermal, chemical, or electrical burn injuries

It primarily affects pediatric and adult patients recovering from partial- or full-thickness thermal, chemical, or electrical burn injuries Pathophysiologically, the loss of the physical epidermal barrier, microvascular disruption, and the presence of an avascular, protein-rich necrotic eschar create an optimal niche for microbial invasion, compounded by local and systemic immunosuppression

Pathophysiologically, the loss of the physical epidermal barrier, microvascular disruption, and the presence of an avascular, protein-rich necrotic eschar create an optimal niche for microbial invasion, compounded by local and systemic immunosuppression

Clinically, it is characterized by localized erythema, swelling, warmth, purulent drainage, unexpected discoloration or rapid separation of the eschar, and the potential conversion of a partial-thickness injury into a full-thickness wound, which may progress to systemic sepsis if tissue invasion occurs