Indication

Kawasaki disease

Kawasaki disease is an acute, self-limited systemic vasculitis primarily affecting medium-sized arteries, most notably the coronary arteries. Read more about Kawasaki disease

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About Kawasaki disease.

Kawasaki disease is an acute, self-limited systemic vasculitis primarily affecting medium-sized arteries, most notably the coronary arteries.

It predominantly develops in infants and young children under five years of age and stands as a leading cause of acquired pediatric heart disease.

Clinically, it is characterized by prolonged high fever, bilateral nonexudative conjunctivitis, mucosal changes such as strawberry tongue and lip erythema, polymorphous rash, induration or erythema of the extremities with desquamation, and cervical lymphadenopathy.

Pathophysiologically, widespread vascular inflammation can weaken arterial wall architecture, predisposing affected individuals to coronary artery dilation, aneurysm formation, thrombosis, and subsequent myocardial ischemia.

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