Lactose intolerance

Lactose intolerance is a gastrointestinal clinical syndrome characterized by digestive symptoms following the ingestion of lactose, the primary disaccharide found in dairy products It arises from a deficiency of lactase-phlorizin hydrolase in the brush border of the small intestine, which impairs the hydrolysis of lactose into glucose and galactose

Lactose intolerance is a gastrointestinal clinical syndrome characterized by digestive symptoms following the ingestion of lactose, the primary disaccharide found in dairy products

When unabsorbed lactose transits into the large intestine, colonic bacterial fermentation produces short-chain fatty acids and gases while exerting an osmotic load that draws fluid into the bowel lumen

When unabsorbed lactose transits into the large intestine, colonic bacterial fermentation produces short-chain fatty acids and gases while exerting an osmotic load that draws fluid into the bowel lumen This pathophysiology manifests clinically in susceptible populations as abdominal pain, cramping, bloating, flatulence, borborygmi, and osmotic diarrhea

This pathophysiology manifests clinically in susceptible populations as abdominal pain, cramping, bloating, flatulence, borborygmi, and osmotic diarrhea